Yesterday I profiled a simple Anchor program against Native and Pinocchio The results were as you would expect - Anchor had additional overhead that could potentially be removed CU-wise: - Anchor - 4503 CU - Native - 2959 CU - Pinocchio - 1526 CU Now to start trimming the fat

You can find the exact code profiled, a longer writeup, and the methodology here:

S/O to @BanRus for the profiler. It was used to conduct this investigation